Supercritical Carbon Dioxide-Assisted Nebulization To Produce Fine Particles Of Stable Protein Formulations
Robert E. Sievers
- American Association of Pharmaceutical Sciences Meeting, Arlington, Virginia, April, 2002
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Key Advantages of Bubble Dryer®
Microbubbles are formed
Reduces thermal degradation of conventional spray drying
Bubbles dry faster than ice cakes in freeze drying (seconds vs. hours)
Redissolution of dried powders is rapid (< 30 sec.)
Simultaneous micronization while drying